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LNA modification available
Locked Nucleic Acid (LNA) is a synthetic nucleic acid analogue containing a bridged, bicyclic sugar moiety. LNA fully complies with Watson- Crick base pairing rules. LNA:DNA hybrids show strongly improved annealing temperatures compared to their DNA:DNA counterparts. Therefore, the major advantage of LNA lies in the design options for primers and probes as the Tm can be finetuned to the needs of the oligonucleotide.
The LNA can be chosen as a modification on our webshop.