GLP-Compliant Sequencing

Microsynth offers high quality double strand sequencing compliant with Good Laboratory Practice (GLP), as specified for non-clinical laboratory studies. Typical applications are submissions to the FDA or patent submissions.

 

All our processes are performed according to proprietary standard operating procedures. To ensure the quality of our GLP-compliant sequencing service, we are routinely assessed by process audits.


Main Service Features and Benefits:

  • You have the choice between 2-fold or 4-fold coverage
  • Each project is guided by a designated study director who oversees all the steps
  • Quality control of incoming DNA
  • Design of sequencing primers every 700 bases (2-fold coverage) or 300-400 bases (4-fold coverage), in-house synthesis of these primers
  • Complete double stranded sequencing of the region of interest with at least 2 or 4 fold coverage
  • Evaluation of each chromatogram. Only sequences with quality values >30 (base call accuracy higher than 99.9%) are used for the assembly
  • Assembly of sequence data
  • Sequence verification against a known reference sequence or de novo sequencing
  • Guaranteed accuracy of final data: 2-fold coverage (>99.999%),  4-fold coverage (>99.99999%)
  • Extended sequencing project documentation
  • Detailed sequencing strategy
  • Quality assurance statement (ISO/IEC 17025 (STS 429))
  • Documents signed by the study director
  • Archiving of samples and data for 10 years (longer times available on request)

 

 

 

 

 

 

 







     



Your Contact:
Write an e-mail to
or call us at
+41-71-722 83 33

to the top