Modified RNA Oligos

Microsynth offers a wide variety of modifications (5’, 3’ and internal) for RNA oligonucleotides. To provide you with a better overview, they have been categorized as
To learn more about key specifications of a particular modification, please see the tables below. To obtain information about our prices, please login to our webshop and download the current price list.

Important - Please Note:
  • If your desired modification is not listed in the following tables, please contact us for availability
  • For modified RNA oligonucleotides, we do not provide minimal or guaranteed delivery amounts
How to Order?
  • Enter our webshop
  • Click on Single Stranded RNA in the "Oligonucleotide" domain
  • Select Normal Entry in order to type or copy/paste the desired sequence information etc. and follow the further instructions
    
RNA Base and/or Sugar-phosphate Backbone Modifications
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Type of Modification

Position

Synthesis Scale [µmol]

Purification

5’

3’

Int.

0.04

0.2

1.0

DES

HPLC

PAGE

2’-O-Methyl-RNA

x

x

x

 

x

x

x

x

x

PTO

 

 

x

 

x

x

x

x

x

2’-Fluor-RNA

x

 

x

 

x

x

x

x

x


  

 Non Fluorescent Modifications
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Type of Modification

Position

Synthesis Scale [µmol]

Purification

5’

3’

Int.

0.04

0.2

1.0

Des

HPLC

PAGE

Aminolink (C6)

x

 

 

 

x

x

 

x

x

Aminolink (C6 or C7)1

 

x

 

 

x

x

 

x

x

Biotin (C6)

x

 

 

 

x

x

 

x

x

Biotin (TEG)

 

x

 

 

x

x

 

x

x

Cholesterol

 

x

 

 

x

x

x

 

x

Digoxigenin

x

x

 

 

x

x

 

x

x

Inverted Thymidine   x     x x x x x
Phosphorylation x x     x x x x x

Spacer C3

x

x

x

 

x

x

x

x

x

Thiol

x

x

 

 

x

x

x

x

x

4-Thio-rU*

x

 

x

 

x

x

x

x

x

* On request                  

 

 Fluorescent or Dye Modifications >>to the top

 

Modifications

Position

Synthesis Scale [µmol]

Purification

5’

3’

Int.

0.04

0.2

1.0

Des

HPLC

PAGE

Cy3/5/5.5/Cy7

x

 

 

 

x

x

 

x

x

FAM

x

x

 

 

x

x

 

x

x

TAMRA

x

x

 

 

x

x

 

x

x

BHQ 1/BHQ 2

 

x

 

 

x

x

 

x

x


 


1  3' Aminolink C7 is used for oligos >50 bases

















































Questions?
Write an e-mail or call us at +41-71-722 83 33


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