RNA Oligos — Modified

Microsynth offers a wide variety of modifications (5’, 3’ and internal) for RNA oligonucleotides. To provide you with a better overview, they have been categorized as

• Modifications involving the RNA Base and/or the Sugar-phosphate Backbone
• Non Fluorescent Modifications
• Fluorescent or Dye Modifications

To learn more about key specifications of a particular modification, please see the tables below. To obtain information about our prices, please login to our webshop and download the current price list.

Important - Please Note:

• If your desired modification is not listed in the following tables, please contact us for availability
• For modified RNA oligonucleotides, we do not provide minimal or guaranteed delivery amounts

How to Order?

• Enter our webshop
• Click on Single Stranded RNA in the "Oligonucleotide" domain
• Select Normal Entry in order to type or copy/paste the desired sequence information etc. and follow the further instructions

    

RNA Base and/or Sugar-phosphate Backbone Modifications

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Type of Modification	Position			Synthesis Scale [µmol]			Purification
	5’	3’	Int.	0.04	0.2	1.0	DES	HPLC	PAGE
2’-O-Methyl-RNA	x	x	x		x	x	x	x	x
PTO			x		x	x	x	x	x
2’-Fluor-RNA	x		x		x	x	x	x	x

  

Non Fluorescent Modifications

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Type of Modification	Position			Synthesis Scale [µmol]			Purification
	5’	3’	Int.	0.04	0.2	1.0	Des	HPLC	PAGE
Aminolink (C6)	x				x	x		x	x
Aminolink (C7)		x			x	x		x	x
Biotin (C6)	x				x	x		x	x
Biotin (TEG)		x			x	x		x	x
Cholesterol		x			x	x	x		x
Digoxigenin	x	x			x	x		x	x
Spacer C3	x	x	x		x	x	x	x	x
Thiol	x	x			x	x	x	x	x
Phosphorylation	x	x			x	x	x	x	x

 



Fluorescent or Dye Modifications

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Modifications	Position			Synthesis Scale [µmol]			Purification
	5’	3’	Int.	0.04	0.2	1.0	Des	HPLC	PAGE
Cy3 / Cy5 / Cy 5.5 / Cy7	x				x	x		x	x
FAM	x	x			x	x		x	x
Tamra	x	x			x	x		x	x
BHQ 1 / BHQ 2		x			x	x		x	x